Boeing, Microsoft, and PENN Entertainment are among the companies making moves in premarket trading.

Boeing’s stock rose 1.5% following an upgrade from Deutsche Bank, which noted the company’s acceleration of aircraft deliveries. Microsoft saw a 0.5% increase after announcing former OpenAI CEO Sam Altman will be joining the tech giant to head a new artificial intelligence research team. Meanwhile, PENN Entertainment gained 4.4% after receiving an upgrade to buy from neutral Bank of America.

On the other hand, Bristol-Myers Squibb’s shares dropped 4.6% in premarket trading due to a delay in gaining expanded approval for their drug Abecma. This delay was announced the drug company, along with 2seventy bio, as the Food and Drug Administration won’t be able to make a decision the target date of Dec. 16.

Krispy Kreme’s shares fell 1.8% following a downgrade JPMorgan to neutral from overweight, citing execution issues. Dutch Bros, however, gained 2% after being upgraded JPMorgan to overweight from neutral.

Iovance Biotherapeutics saw a 9.7% increase in their stock after Goldman Sachs initiated coverage with a buy rating and a $12 price target. The biopharmaceutical firm is developing autologous tumor-infiltrating lymphocyte therapies for solid tumor cancers.

Vale, the Brazil-based metal and mining company, added 2.6% following an upgrade Bank of America. The bank sees higher iron ore prices driving high free-cash-flow generation.

Lastly, Chegg’s stock shed 5.4% after being downgraded Morgan Stanley, and United Rentals dropped over 4% after a director disclosed selling 630 shares.

These fluctuations in premarket trading demonstrate the impact of various upgrades, downgrades, and delays in the stock market.

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